Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival

Colony-stimulating factor 1 (CSF1) and interleukin-34 (IL-34) are functional ligands of the CSF1 receptor (CSF1R) and thus are key regulators of the monocyte/macrophage lineage. We discovered that systemic administration of human recombinant CSF1 ameliorates memory deficits in a transgenic mouse mod...

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Detalles Bibliográficos
Autores principales: Luo, Jian, Elwood, Fiona, Britschgi, Markus, Villeda, Saul, Zhang, Hui, Ding, Zhaoqing, Zhu, Liyin, Alabsi, Haitham, Getachew, Ruth, Narasimhan, Ramya, Wabl, Rafael, Fainberg, Nina, James, Michelle L., Wong, Gordon, Relton, Jane, Gambhir, Sanjiv S., Pollard, Jeffrey W., Wyss-Coray, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549715/
https://www.ncbi.nlm.nih.gov/pubmed/23296467
http://dx.doi.org/10.1084/jem.20120412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549715/
https://www.ncbi.nlm.nih.gov/pubmed/23296467
http://dx.doi.org/10.1084/jem.20120412

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