Poly(ADP-ribose) polymerase 1 regulates nuclear reprogramming and promotes iPSC generation without c-Myc

Poly(ADP-ribose) polymerase 1 (Parp1) catalyzes poly(ADP-ribosylation) (PARylation) and induces replication networks involved in multiple nuclear events. Using mass spectrometry and Western blotting, Parp1 and PARylation activity were intensively detected in induced pluripotent stem cells (iPSCs) an...

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Detalles Bibliográficos
Autores principales: Chiou, Shih-Hwa, Jiang, Bo-Hwa, Yu, Yung-Luen, Chou, Shih-Jie, Tsai, Ping-Hsing, Chang, Wei-Chao, Chen, Liang-Kung, Chen, Li-Hsin, Chien, Yueh, Chiou, Guang-Yuh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549716/
https://www.ncbi.nlm.nih.gov/pubmed/23277454
http://dx.doi.org/10.1084/jem.20121044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549716/
https://www.ncbi.nlm.nih.gov/pubmed/23277454
http://dx.doi.org/10.1084/jem.20121044

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