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Up-regulation of a death receptor renders antiviral T cells susceptible to NK cell–mediated deletion

Antiviral T cell responses in hepatotropic viral infections such as hepatitis B virus (HBV) are profoundly diminished and prone to apoptotic deletion. In this study, we investigate whether the large population of activated NK cells in the human liver contributes to this process. We show that in vitr...

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Detalles Bibliográficos
Autores principales: Peppa, Dimitra, Gill, Upkar S., Reynolds, Gary, Easom, Nicholas J.W., Pallett, Laura J., Schurich, Anna, Micco, Lorenzo, Nebbia, Gaia, Singh, Harsimran D., Adams, David H., Kennedy, Patrick T.F., Maini, Mala K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549717/
https://www.ncbi.nlm.nih.gov/pubmed/23254287
http://dx.doi.org/10.1084/jem.20121172