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Up-regulation of a death receptor renders antiviral T cells susceptible to NK cell–mediated deletion
Antiviral T cell responses in hepatotropic viral infections such as hepatitis B virus (HBV) are profoundly diminished and prone to apoptotic deletion. In this study, we investigate whether the large population of activated NK cells in the human liver contributes to this process. We show that in vitr...
Autores principales: | Peppa, Dimitra, Gill, Upkar S., Reynolds, Gary, Easom, Nicholas J.W., Pallett, Laura J., Schurich, Anna, Micco, Lorenzo, Nebbia, Gaia, Singh, Harsimran D., Adams, David H., Kennedy, Patrick T.F., Maini, Mala K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549717/ https://www.ncbi.nlm.nih.gov/pubmed/23254287 http://dx.doi.org/10.1084/jem.20121172 |
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