Global analysis of B cell selection using an immunoglobulin light chain–mediated model of autoreactivity

The important subtleties of B cell tolerance are best understood in a diverse immunoglobulin (Ig) repertoire context encoding a full spectrum of autoreactivity. To achieve this, we used mice expressing Igκ transgenes that confer varying degrees of autoreactivity within a diverse heavy chain (HC) rep...

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Detalles Bibliográficos
Autores principales: Andrews, Sarah F., Zhang, Qingzhao, Lim, Samuel, Li, Lie, Lee, Jane-Hwei, Zheng, Nai-Ying, Huang, Min, Taylor, William M., Farris, A. Darise, Ni, Dongyao, Meng, Wenzhao, Luning Prak, Eline T., Wilson, Patrick C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549719/
https://www.ncbi.nlm.nih.gov/pubmed/23267014
http://dx.doi.org/10.1084/jem.20120525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549719/
https://www.ncbi.nlm.nih.gov/pubmed/23267014
http://dx.doi.org/10.1084/jem.20120525

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