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Diversification of the expanded teleost-specific toll-like receptor family in Atlantic cod, Gadus morhua

BACKGROUND: Toll-like receptors (Tlrs) are major molecular pattern recognition receptors of the innate immune system. Atlantic cod (Gadus morhua) is the first vertebrate known to have lost most of the mammalian Tlr orthologues, particularly all bacterial recognising and other cell surface Tlrs. On t...

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Detalles Bibliográficos
Autores principales: Sundaram, Arvind YM, Kiron, Viswanath, Dopazo, Joaquín, Fernandes, Jorge MO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549756/
https://www.ncbi.nlm.nih.gov/pubmed/23273344
http://dx.doi.org/10.1186/1471-2148-12-256