Improved moderation for gene-wise variance estimation in RNA-Seq via the exploitation of external information

BACKGROUND: The cost of RNA-Seq has been decreasing over the last few years. Despite this, experiments with four or less biological replicates are still quite common. Estimating the variances of gene expression estimates becomes both a challenging and interesting problem in these situations of low r...

Descripción completa

Detalles Bibliográficos
Autores principales: Patrick, Ellis, Buckley, Michael, Lin, David Ming, Yang, Yee Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549800/
https://www.ncbi.nlm.nih.gov/pubmed/23368783
http://dx.doi.org/10.1186/1471-2164-14-S1-S9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549800/
https://www.ncbi.nlm.nih.gov/pubmed/23368783
http://dx.doi.org/10.1186/1471-2164-14-S1-S9

Ejemplares similares