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Improved moderation for gene-wise variance estimation in RNA-Seq via the exploitation of external information
BACKGROUND: The cost of RNA-Seq has been decreasing over the last few years. Despite this, experiments with four or less biological replicates are still quite common. Estimating the variances of gene expression estimates becomes both a challenging and interesting problem in these situations of low r...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549800/ https://www.ncbi.nlm.nih.gov/pubmed/23368783 http://dx.doi.org/10.1186/1471-2164-14-S1-S9 |