FitSearch: a robust way to interpret a yeast fitness profile in terms of drug's mode-of-action

BACKGROUND: Yeast deletion-mutant collections have been successfully used to infer the mode-of-action of drugs especially by profiling chemical-genetic and genetic-genetic interactions on a genome-wide scale. Although tens of thousands of those profiles are publicly available, a lack of an accurate...

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Detalles Bibliográficos
Autores principales: Lee, Minho, Han, Sangjo, Chang, Hyeshik, Kwak, Youn-Sig, Weller, David M, Kim, Dongsup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549813/
https://www.ncbi.nlm.nih.gov/pubmed/23368702
http://dx.doi.org/10.1186/1471-2164-14-S1-S6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549813/
https://www.ncbi.nlm.nih.gov/pubmed/23368702
http://dx.doi.org/10.1186/1471-2164-14-S1-S6

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