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FitSearch: a robust way to interpret a yeast fitness profile in terms of drug's mode-of-action
BACKGROUND: Yeast deletion-mutant collections have been successfully used to infer the mode-of-action of drugs especially by profiling chemical-genetic and genetic-genetic interactions on a genome-wide scale. Although tens of thousands of those profiles are publicly available, a lack of an accurate...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549813/ https://www.ncbi.nlm.nih.gov/pubmed/23368702 http://dx.doi.org/10.1186/1471-2164-14-S1-S6 |