Sequence-only evolutionary and predicted structural features for the prediction of stability changes in protein mutants

BACKGROUND: Even a single amino acid substitution in a protein sequence may result in significant changes in protein stability, structure, and therefore in protein function as well. In the post-genomic era, computational methods for predicting stability changes from only the sequence of a protein ar...

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Detalles Bibliográficos
Autores principales: Folkman, Lukas, Stantic, Bela, Sattar, Abdul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549838/
https://www.ncbi.nlm.nih.gov/pubmed/23369338
http://dx.doi.org/10.1186/1471-2105-14-S2-S6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549838/
https://www.ncbi.nlm.nih.gov/pubmed/23369338
http://dx.doi.org/10.1186/1471-2105-14-S2-S6

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