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Aberrant DNA methylation profiles in the premature aging disorders Hutchinson-Gilford Progeria and Werner syndrome

DNA methylation gradiently changes with age and is likely to be involved in aging-related processes with subsequent phenotype changes and increased susceptibility to certain diseases. The Hutchinson-Gilford Progeria (HGP) and Werner Syndrome (WS) are two premature aging diseases showing features of...

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Detalles Bibliográficos
Autores principales: Heyn, Holger, Moran, Sebastian, Esteller, Manel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549877/
https://www.ncbi.nlm.nih.gov/pubmed/23257959
http://dx.doi.org/10.4161/epi.23366