Attenuation of Rhes Activity Significantly Delays the Appearance of Behavioral Symptoms in a Mouse Model of Huntington's Disease

Huntington's disease (HD) is a neuropsychiatric disorder characterized by choreiform movement of the limbs, cognitive disability, psychosis and dementia. It is invariably associated with an abnormally long CAG expansion within the IT15 gene on human chromosome 4. Although the mutant huntingtin...

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Detalles Bibliográficos
Autores principales: Baiamonte, Brandon A., Lee, Franklin A., Brewer, Steve T., Spano, Daniela, LaHoste, Gerald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549908/
https://www.ncbi.nlm.nih.gov/pubmed/23349722
http://dx.doi.org/10.1371/journal.pone.0053606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549908/
https://www.ncbi.nlm.nih.gov/pubmed/23349722
http://dx.doi.org/10.1371/journal.pone.0053606

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