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Phosphorylation of STAT-1 Serine 727 Is Prolonged in HLA-B27-Expressing Human Monocytic Cells

A tissue antigen, HLA-B27, is strongly associated with a group of rheumatic diseases called spondyloarthritides. Despite the intensive research, the exact role of HLA-B27 in the pathogenesis of these diseases is still unclear. Here we studied whether HLA-B27 modulates the phosphorylation of signal t...

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Detalles Bibliográficos
Autores principales: Ruuska, Marja, Sahlberg, Anna S., Granfors, Kaisa, Penttinen, Markus A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549911/
https://www.ncbi.nlm.nih.gov/pubmed/23349666
http://dx.doi.org/10.1371/journal.pone.0050684