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Identification of the Cancer Cell Proliferation and Survival Functions of proHB-EGF by Using an Anti-HB-EGF Antibody

PURPOSE: Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a member of the epidermal growth factor family. The membrane-bound proHB-EGF is known to be a precursor of the soluble form of HB-EGF (sHB-EGF), which promotes cell proliferation and survival. While the functions of sHB-...

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Detalles Bibliográficos
Autores principales: Sato, Shuji, Kamada, Hiroko, Watanabe, Takahiro, Tsuji, Isamu, Fan, Jinhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549951/
https://www.ncbi.nlm.nih.gov/pubmed/23349913
http://dx.doi.org/10.1371/journal.pone.0054509