Two Functional Motifs Define the Interaction, Internalization and Toxicity of the Cell-Penetrating Antifungal Peptide PAF26 on Fungal Cells

The synthetic, cell penetrating hexapeptide PAF26 (RKKWFW) is antifungal at low micromolar concentrations and has been proposed as a model for cationic, cell-penetrating antifungal peptides. Its short amino acid sequence facilitates the analysis of its structure-activity relationships using the fung...

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Detalles Bibliográficos
Autores principales: Muñoz, Alberto, Harries, Eleonora, Contreras-Valenzuela, Adriana, Carmona, Lourdes, Read, Nick D., Marcos, Jose F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549957/
https://www.ncbi.nlm.nih.gov/pubmed/23349973
http://dx.doi.org/10.1371/journal.pone.0054813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549957/
https://www.ncbi.nlm.nih.gov/pubmed/23349973
http://dx.doi.org/10.1371/journal.pone.0054813

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