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Two Functional Motifs Define the Interaction, Internalization and Toxicity of the Cell-Penetrating Antifungal Peptide PAF26 on Fungal Cells
The synthetic, cell penetrating hexapeptide PAF26 (RKKWFW) is antifungal at low micromolar concentrations and has been proposed as a model for cationic, cell-penetrating antifungal peptides. Its short amino acid sequence facilitates the analysis of its structure-activity relationships using the fung...
Autores principales: | Muñoz, Alberto, Harries, Eleonora, Contreras-Valenzuela, Adriana, Carmona, Lourdes, Read, Nick D., Marcos, Jose F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549957/ https://www.ncbi.nlm.nih.gov/pubmed/23349973 http://dx.doi.org/10.1371/journal.pone.0054813 |
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