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Perlecan regulates bidirectional Wnt signaling at the Drosophila neuromuscular junction

Heparan sulfate proteoglycans (HSPGs) play pivotal roles in the regulation of Wnt signaling activity in several tissues. At the Drosophila melanogaster neuromuscular junction (NMJ), Wnt/Wingless (Wg) regulates the formation of both pre- and postsynaptic structures; however, the mechanism balancing s...

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Detalles Bibliográficos
Autores principales: Kamimura, Keisuke, Ueno, Kohei, Nakagawa, Jun, Hamada, Rie, Saitoe, Minoru, Maeda, Nobuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549968/
https://www.ncbi.nlm.nih.gov/pubmed/23319599
http://dx.doi.org/10.1083/jcb.201207036