Promoter Hypermethylation of ARID1A Gene Is Responsible for Its Low mRNA Expression in Many Invasive Breast Cancers

ARID1A (AT-rich interactive domain 1A) has recently been identified as a tumor suppressor gene. Its mRNA expression is significantly low in many breast cancers; this is often associated with more aggressive phenotypes. However, the underlying molecular mechanism for its low expression has not been f...

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Detalles Bibliográficos
Autores principales: Zhang, Xianyu, Sun, Qian, Shan, Ming, Niu, Ming, Liu, Tong, Xia, Bingshu, Liang, Xiaoshuan, Wei, Wei, Sun, Shanshan, Zhang, Youxue, Liu, Xiaolong Sean, Song, Qingbin, Yang, Yanmei, Ma, Yuyan, Liu, Yang, Yang, Long, Ren, Yanlv, Zhang, Guoqiang, Pang, Da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549982/
https://www.ncbi.nlm.nih.gov/pubmed/23349767
http://dx.doi.org/10.1371/journal.pone.0053931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549982/
https://www.ncbi.nlm.nih.gov/pubmed/23349767
http://dx.doi.org/10.1371/journal.pone.0053931

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