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A novel mouse model that develops spontaneous arthritis and is predisposed towards atherosclerosis

OBJECTIVES: Patients with rheumatoid arthritis (RA) have a reduced life expectancy due to increased cardiovascular disease. The lack of a suitable animal model resembling both RA and atherosclerosis has hindered studies demonstrating a direct link between systemic inflammation in RA and the developm...

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Detalles Bibliográficos
Autores principales: Rose, Shawn, Eren, Mesut, Murphy, Sheila, Zhang, Heng, Thaxton, Colby Shad, Chowaniec, Jaime, Waters, Emily A, Meade, Thomas J, Vaughan, Douglas E, Perlman, Harris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551222/
https://www.ncbi.nlm.nih.gov/pubmed/22736097
http://dx.doi.org/10.1136/annrheumdis-2012-201431