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Targeted delivery of cytokine therapy to rheumatoid tissue by a synovial targeting peptide

OBJECTIVES: The synovial endothelium targeting peptide (SyETP) CKSTHDRLC has been identified previously and was shown to preferentially localise to synovial xenografts in the human/severe combined immunodeficient (SCID) mouse chimera model of rheumatoid arthritis (RA). The objective of the current w...

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Detalles Bibliográficos
Autores principales: Wythe, Sarah E, DiCara, Danielle, Taher, Taher E I, Finucane, Ciara M, Jones, Rita, Bombardieri, Michele, Man, Y K Stella, Nissim, Ahuva, Mather, Stephen J, Chernajovsky, Yuti, Pitzalis, Costantino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551226/
https://www.ncbi.nlm.nih.gov/pubmed/22843486
http://dx.doi.org/10.1136/annrheumdis-2012-201457