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Potential use of Folate-appended Methyl-β-Cyclodextrin as an Anticancer Agent

To obtain a tumor cell-selectivity of methyl-β-cyclodextrin (M-β-CyD), we newly synthesized folate-appended M-β-CyD (FA-M-β-CyD), and evaluated the potential of FA-M-β-CyD as a novel anticancer agent in vitro and in vivo. Potent antitumor activity and cellular association of FA-M-β-CyD were higher t...

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Detalles Bibliográficos
Autores principales: Onodera, Risako, Motoyama, Keiichi, Okamatsu, Ayaka, Higashi, Taishi, Arima, Hidetoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551233/
https://www.ncbi.nlm.nih.gov/pubmed/23346361
http://dx.doi.org/10.1038/srep01104