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Chromatin modifications and the DNA damage response to ionizing radiation

In order to survive, cells have evolved highly effective repair mechanisms to deal with the potentially lethal DNA damage produced by exposure to endogenous as well as exogenous agents. Ionizing radiation exposure induces highly lethal DNA damage, especially DNA double-strand breaks (DSBs), that is...

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Detalles Bibliográficos
Autores principales: Kumar, Rakesh, Horikoshi, Nobuo, Singh, Mayank, Gupta, Arun, Misra, Hari S., Albuquerque, Kevin, Hunt, Clayton R., Pandita, Tej K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551241/
https://www.ncbi.nlm.nih.gov/pubmed/23346550
http://dx.doi.org/10.3389/fonc.2012.00214