Efficient Internalization of MHC I Requires Lysine-11 and Lysine-63 Mixed Linkage Polyubiquitin Chains

The downregulation of cell surface receptors by endocytosis is a fundamental requirement for the termination of signalling responses and ubiquitination is a critical regulatory step in receptor regulation. The K5 gene product of Kaposi's sarcoma-associated herpesvirus is an E3 ligase that ubiqu...

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Detalles Bibliográficos
Autores principales: Boname, Jessica M, Thomas, Mair, Stagg, Helen R, Xu, Ping, Peng, Junmin, Lehner, Paul J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551259/
https://www.ncbi.nlm.nih.gov/pubmed/19948006
http://dx.doi.org/10.1111/j.1600-0854.2009.01011.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551259/
https://www.ncbi.nlm.nih.gov/pubmed/19948006
http://dx.doi.org/10.1111/j.1600-0854.2009.01011.x

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