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Association of BACE1 Gene Polymorphism with Cerebellar Volume but Not Cognitive Function in Normal Individuals

AIMS: β-Site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1) is a biological and positional candidate gene for Alzheimer's disease (AD). Previous studies found that BACE1-null mice had impaired performance on cognition and neurodegeneration during the aging process. Additionally, a sy...

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Detalles Bibliográficos
Autores principales: Tsai, Alex, Huang, Chu-Chung, Yang, Albert C., Liu, Mu-En, Tu, Pei-Chi, Hong, Chen-Jee, Liou, Ying-Jay, Chen, Jin-Fan, Lin, Ching-Po, Tsai, Shih-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551403/
https://www.ncbi.nlm.nih.gov/pubmed/23341828
http://dx.doi.org/10.1159/000345980