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Metallochaperones Regulate Intracellular Copper Levels

Copper (Cu) is an important enzyme co-factor that is also extremely toxic at high intracellular concentrations, making active efflux mechanisms essential for preventing Cu accumulation. Here, we have investigated the mechanistic role of metallochaperones in regulating Cu efflux. We have constructed...

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Detalles Bibliográficos
Autores principales: Pang, W. Lee, Kaur, Amardeep, Ratushny, Alexander V., Cvetkovic, Aleksandar, Kumar, Sunil, Pan, Min, Arkin, Adam P., Aitchison, John D., Adams, Michael W. W., Baliga, Nitin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551603/
https://www.ncbi.nlm.nih.gov/pubmed/23349626
http://dx.doi.org/10.1371/journal.pcbi.1002880