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Metallochaperones Regulate Intracellular Copper Levels
Copper (Cu) is an important enzyme co-factor that is also extremely toxic at high intracellular concentrations, making active efflux mechanisms essential for preventing Cu accumulation. Here, we have investigated the mechanistic role of metallochaperones in regulating Cu efflux. We have constructed...
Autores principales: | Pang, W. Lee, Kaur, Amardeep, Ratushny, Alexander V., Cvetkovic, Aleksandar, Kumar, Sunil, Pan, Min, Arkin, Adam P., Aitchison, John D., Adams, Michael W. W., Baliga, Nitin S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551603/ https://www.ncbi.nlm.nih.gov/pubmed/23349626 http://dx.doi.org/10.1371/journal.pcbi.1002880 |
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