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Antisense-mediated isoform switching of steroid receptor coactivator-1 in the central nucleus of the amygdala of the mouse brain

BACKGROUND: Antisense oligonucleotide (AON)-mediated exon skipping is a powerful tool to manipulate gene expression. In the present study we investigated the potential of exon skipping by local injection in the central nucleus of the amygdala (CeA) of the mouse brain. As proof of principle we target...

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Detalles Bibliográficos
Autores principales: Zalachoras, Ioannis, Grootaers, Gwendolynn, van Weert, Lisa TCM, Aubert, Yves, de Kreij, Suzanne R, Datson, Nicole A, van Roon-Mom, Willeke MC, Aartsma-Rus, Annemieke, Meijer, Onno C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551673/
https://www.ncbi.nlm.nih.gov/pubmed/23294837
http://dx.doi.org/10.1186/1471-2202-14-5