Sildenafil restores endothelial function in the apolipoprotein E knockout mouse

BACKGROUND: Atherosclerosis is an inflammatory process of the arterial walls and is initiated by endothelial dysfunction accompanied by an imbalance in the production of reactive oxygen species (ROS) and nitric oxide (NO). Sildenafil, a selective phosphodiesterase-5 (PDE5) inhibitor used for erectil...

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Detalles Bibliográficos
Autores principales: Balarini, Camille M, Leal, Marcos A, Gomes, Isabele B S, Pereira, Thiago M C, Gava, Agata L, Meyrelles, Silvana S, Vasquez, Elisardo C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551739/
https://www.ncbi.nlm.nih.gov/pubmed/23289368
http://dx.doi.org/10.1186/1479-5876-11-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551739/
https://www.ncbi.nlm.nih.gov/pubmed/23289368
http://dx.doi.org/10.1186/1479-5876-11-3

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