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HIV-1 Fusion Is Blocked through Binding of GB Virus C E2D Peptides to the HIV-1 gp41 Disulfide Loop

A strategy for antiviral drug discovery is the elucidation and imitation of viral interference mechanisms. HIV-1 patients benefit from a coinfection with GB Virus C (GBV-C), since HIV-positive individuals with long-term GBV-C viraemia show better survival rates than HIV-1 patients without persisting...

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Detalles Bibliográficos
Autores principales: Eissmann, Kristin, Mueller, Sebastian, Sticht, Heinrich, Jung, Susan, Zou, Peng, Jiang, Shibo, Gross, Andrea, Eichler, Jutta, Fleckenstein, Bernhard, Reil, Heide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551756/
https://www.ncbi.nlm.nih.gov/pubmed/23349893
http://dx.doi.org/10.1371/journal.pone.0054452