Blockade of phospholipid scramblase 1 with its N-terminal domain antibody reduces tumorigenesis of colorectal carcinomas in vitro and in vivo

BACKGROUND: Membrane-bound phospholipid scramblase 1 (PLSCR1) is involved in both lipid trafficking and cell signaling. Previously, we showed that PLSCR1 is overexpressed in many colorectal carcinomas (CRCs). In the present study, we investigated the tumorigenic role of PLSCR1 in CRC and suggest tha...

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Detalles Bibliográficos
Autores principales: Fan, Chung-Wei, Chen, Chun-Yu, Chen, Kuei-Tien, Shen, Chia-Rui, Kuo, Yung-Bin, Chen, Ya-Shan, Chou, Yeh-Pin, Wei, Wei-Shan, Chan, Err-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551821/
https://www.ncbi.nlm.nih.gov/pubmed/23259795
http://dx.doi.org/10.1186/1479-5876-10-254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551821/
https://www.ncbi.nlm.nih.gov/pubmed/23259795
http://dx.doi.org/10.1186/1479-5876-10-254

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