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Co-Culture of Hematopoietic Stem/Progenitor Cells with Human Osteblasts Favours Mono/Macrophage Differentiation at the Expense of the Erythroid Lineage

Hematopoietic stem cells (HSCs) are located in the bone marrow in a specific microenvironment referred as the hematopoietic stem cell niche, where HSCs interact with a variety of stromal cells. Though several components of the stem cell niche have been identified, the regulatory mechanisms through w...

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Detalles Bibliográficos
Autores principales: Salati, Simona, Lisignoli, Gina, Manferdini, Cristina, Pennucci, Valentina, Zini, Roberta, Bianchi, Elisa, Norfo, Ruggiero, Facchini, Andrea, Ferrari, Sergio, Manfredini, Rossella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551919/
https://www.ncbi.nlm.nih.gov/pubmed/23349713
http://dx.doi.org/10.1371/journal.pone.0053496