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Allelic Expression Imbalance of JAK2 V617F Mutation in BCR-ABL Negative Myeloproliferative Neoplasms

The discovery of a single point mutation in the JAK2 gene in patients with BCR/ABL-negative myeloproliferative neoplasms (MPNs) has not only brought new insights and pathogenesis, but also has made the diagnosis of MPNs much easier. Although, to date, several mechanisms for the contribution of singl...

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Detalles Bibliográficos
Autores principales: Kim, Hye-Ran, Choi, Hyun-Jung, Kim, Yeo-Kyeoung, Kim, Hyeoung-Joon, Shin, Jong-Hee, Suh, Soon-Pal, Ryang, Dong-Wook, Shin, Myung-Geun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551963/
https://www.ncbi.nlm.nih.gov/pubmed/23349688
http://dx.doi.org/10.1371/journal.pone.0052518