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IKKβ in Myeloid Cells Controls the Host Response to Lethal and Sublethal Francisella tularensis LVS Infection

BACKGROUND: The NF-κB activating kinases, IKKα and IKKβ, are key regulators of inflammation and immunity in response to infection by a variety of pathogens. Both IKKα and IKKβ have been reported to modulate either pro- or anti- inflammatory programs, which may be specific to the infectious organism...

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Detalles Bibliográficos
Autores principales: Samaniego, Sylvia, Marcu, Kenneth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551972/
https://www.ncbi.nlm.nih.gov/pubmed/23349802
http://dx.doi.org/10.1371/journal.pone.0054124