Allosteric regulation of DegS protease subunits though a shared energy landscape

The PDZ domains of the trimeric DegS protease bind unassembled outer-membrane proteins (OMPs) that accumulate in the E. coli periplasm. This cooperative binding reaction triggers a proteolytic cascade that activates a transcriptional stress response. To dissect the mechanism of allosteric activation...

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Detalles Bibliográficos
Autores principales: Mauldin, Randall V., Sauer, Robert T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551985/
https://www.ncbi.nlm.nih.gov/pubmed/23201899
http://dx.doi.org/10.1038/nchembio.1135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551985/
https://www.ncbi.nlm.nih.gov/pubmed/23201899
http://dx.doi.org/10.1038/nchembio.1135

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