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Interaction between p68 RNA helicase and Ca2(+)-calmodulin promotes cell migration and metastasis

p68 RNA helicase is a prototypical RNA helicase. Here we present evidence to show that, by interacting with Ca-calmodulin (CaM), p68 plays a role in cancer metastasis and cell migration. A peptide fragment that spans the IQ motif of p68 strongly inhibits cancer metastasis in two different animal mod...

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Detalles Bibliográficos
Autores principales: Wang, Haizhen, Gao, Xueliang, Yang, Jenny J., Liu, Zhi-Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552336/
https://www.ncbi.nlm.nih.gov/pubmed/23322042
http://dx.doi.org/10.1038/ncomms2345