Cargando…
Interaction between p68 RNA helicase and Ca2(+)-calmodulin promotes cell migration and metastasis
p68 RNA helicase is a prototypical RNA helicase. Here we present evidence to show that, by interacting with Ca-calmodulin (CaM), p68 plays a role in cancer metastasis and cell migration. A peptide fragment that spans the IQ motif of p68 strongly inhibits cancer metastasis in two different animal mod...
Autores principales: | Wang, Haizhen, Gao, Xueliang, Yang, Jenny J., Liu, Zhi-Ren |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552336/ https://www.ncbi.nlm.nih.gov/pubmed/23322042 http://dx.doi.org/10.1038/ncomms2345 |
Ejemplares similares
-
P68 RNA Helicase Is A Nucleocytoplasm Shuttling Protein
por: Wang, Haizhen, et al.
Publicado: (2009) -
P68 RNA Helicase facilitates Breast Cancer progression by promoting Proliferation and Migration via PDGFR-β/AR axis
por: Panchbhai, Neha, et al.
Publicado: (2021) -
Phosphorylated P68 RNA Helicase Activates Snail1 Transcription by Promoting HDAC1 Dissociation from the Snail1 Promoter
por: Carter, Christie L., et al.
Publicado: (2010) -
Phosphorylation of P68 RNA Helicase by P38 MAP kinase contributes to colon cancer cells apoptosis induced by oxaliplatin
por: Dey, Heena, et al.
Publicado: (2012) -
The p68 and p72 DEAD box RNA helicases interact with HDAC1 and repress transcription in a promoter-specific manner
por: Wilson, Brian J, et al.
Publicado: (2004)