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Development of a novel DNA sequencing method not only for hepatitis B virus genotyping but also for drug resistant mutation detection
BACKGROUND: In HBV-infected patients, different genotypes of the hepatitis B virus influence liver disease progression and response to antiviral therapy. Moreover, long-term antiviral therapy will eventually select for drug-resistant mutants. Detection of mutations associated to antiviral therapy an...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552692/ https://www.ncbi.nlm.nih.gov/pubmed/23369292 http://dx.doi.org/10.1186/1755-8794-6-S1-S15 |