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Development of a novel DNA sequencing method not only for hepatitis B virus genotyping but also for drug resistant mutation detection

BACKGROUND: In HBV-infected patients, different genotypes of the hepatitis B virus influence liver disease progression and response to antiviral therapy. Moreover, long-term antiviral therapy will eventually select for drug-resistant mutants. Detection of mutations associated to antiviral therapy an...

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Detalles Bibliográficos
Autores principales: Wang, Fanjun, Lu, Lili, Yu, Changshun, Lv, Zhanwu, Luo, Xuelian, Wan, Chao, Hu, Zhaohui, Zhu, Qinyi, Deng, Youping, Zhang, Chuyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552692/
https://www.ncbi.nlm.nih.gov/pubmed/23369292
http://dx.doi.org/10.1186/1755-8794-6-S1-S15