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Malaria resistance genes are associated with the levels of IgG subclasses directed against Plasmodium falciparum blood-stage antigens in Burkina Faso

BACKGROUND: HBB, IL4, IL12, TNF, LTA, NCR3 and FCGR2A polymorphisms have been associated with malaria resistance in humans, whereas cytophilic immunoglobulin G (IgG) antibodies are thought to play a critical role in immune protection against asexual blood stages of the parasite. Furthermore, HBB, IL...

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Detalles Bibliográficos
Autores principales: Afridi, Sarwat, Atkinson, Alexandre, Garnier, Séverine, Fumoux, Francis, Rihet, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552815/
https://www.ncbi.nlm.nih.gov/pubmed/22947458
http://dx.doi.org/10.1186/1475-2875-11-308