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Oxygen Tension Modulates Differentiation and Primary Macrophage Functions in the Human Monocytic THP-1 Cell Line

The human THP-1 cell line is widely used as an in vitro model system for studying macrophage differentiation and function. Conventional culture conditions for these cells consist of ambient oxygen pressure (∼20% v/v) and medium supplemented with the thiol 2-mercaptoethanol (2-ME) and serum. In consi...

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Detalles Bibliográficos
Autores principales: Grodzki, Ana Cristina G., Giulivi, Cecilia, Lein, Pamela J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552948/
https://www.ncbi.nlm.nih.gov/pubmed/23355903
http://dx.doi.org/10.1371/journal.pone.0054926