Sequence-based in silico analysis of well studied Hepatitis C Virus epitopes and their variants in other genotypes (particularly genotype 5a) against South African human leukocyte antigen backgrounds

BACKGROUND: Host genetics influence the outcome of HCV disease. HCV is also highly mutable and escapes host immunity. HCV genotypes are geographically distributed and HCV subtypes have been shown to have distinct repertoires of HLA-restricted viral epitopes which explains the lack of cross protectio...

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Detalles Bibliográficos
Autores principales: Prabdial-Sing, Nishi, Puren, Adrian J, Bowyer, Sheila M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552980/
https://www.ncbi.nlm.nih.gov/pubmed/23227878
http://dx.doi.org/10.1186/1471-2172-13-67

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552980/
https://www.ncbi.nlm.nih.gov/pubmed/23227878
http://dx.doi.org/10.1186/1471-2172-13-67

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