Albumin Stimulates the Activity of the Human UDP-Glucuronosyltransferases 1A7, 1A8, 1A10, 2A1 and 2B15, but the Effects Are Enzyme and Substrate Dependent

Human UDP-glucuronosyltransferases (UGTs) are important enzymes in metabolic elimination of endo- and xenobiotics. It was recently shown that addition of fatty acid free bovine serum albumin (BSA) significantly enhances in vitro activities of UGTs, a limiting factor in in vitro–in vivo extrapolation...

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Detalles Bibliográficos
Autores principales: Manevski, Nenad, Troberg, Johanna, Svaluto-Moreolo, Paolo, Dziedzic, Klaudyna, Yli-Kauhaluoma, Jari, Finel, Moshe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553014/
https://www.ncbi.nlm.nih.gov/pubmed/23372764
http://dx.doi.org/10.1371/journal.pone.0054767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553014/
https://www.ncbi.nlm.nih.gov/pubmed/23372764
http://dx.doi.org/10.1371/journal.pone.0054767

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