Cis and Trans Regulatory Mechanisms Control AP2-Mediated B Cell Receptor Endocytosis via Select Tyrosine-Based Motifs

Following antigen recognition, B cell receptor (BCR)-mediated endocytosis is the first step of antigen processing and presentation to CD4+ T cells, a crucial component of the initiation and control of the humoral immune response. Despite this, the molecular mechanism of BCR internalization is poorly...

Descripción completa

Detalles Bibliográficos
Autores principales: Busman-Sahay, Kathleen, Drake, Lisa, Sitaram, Anand, Marks, Michael, Drake, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553015/
https://www.ncbi.nlm.nih.gov/pubmed/23372794
http://dx.doi.org/10.1371/journal.pone.0054938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553015/
https://www.ncbi.nlm.nih.gov/pubmed/23372794
http://dx.doi.org/10.1371/journal.pone.0054938

Ejemplares similares