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Investigating Multiple Candidate Genes and Nutrients in the Folate Metabolism Pathway to Detect Genetic and Nutritional Risk Factors for Lung Cancer

PURPOSE: Folate metabolism, with its importance to DNA repair, provides a promising region for genetic investigation of lung cancer risk. This project investigates genes (MTHFR, MTR, MTRR, CBS, SHMT1, TYMS), folate metabolism related nutrients (B vitamins, methionine, choline, and betaine) and their...

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Detalles Bibliográficos
Autores principales: Swartz, Michael D., Peterson, Christine B., Lupo, Philip J., Wu, Xifeng, Forman, Michele R., Spitz, Margaret R., Hernandez, Ladia M., Vannucci, Marina, Shete, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553105/
https://www.ncbi.nlm.nih.gov/pubmed/23372658
http://dx.doi.org/10.1371/journal.pone.0053475