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A Single Cell Level Based Method for Copy Number Variation Analysis by Low Coverage Massively Parallel Sequencing

Copy number variations (CNVs), a common genomic mutation associated with various diseases, are important in research and clinical applications. Whole genome amplification (WGA) and massively parallel sequencing have been applied to single cell CNVs analysis, which provides new insight for the fields...

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Detalles Bibliográficos
Autores principales: Zhang, Chunlei, Zhang, Chunsheng, Chen, Shengpei, Yin, Xuyang, Pan, Xiaoyu, Lin, Ge, Tan, Yueqiu, Tan, Ke, Xu, Zhengfeng, Hu, Ping, Li, Xuchao, Chen, Fang, Xu, Xun, Li, Yingrui, Zhang, Xiuqing, Jiang, Hui, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553135/
https://www.ncbi.nlm.nih.gov/pubmed/23372689
http://dx.doi.org/10.1371/journal.pone.0054236