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A Single Cell Level Based Method for Copy Number Variation Analysis by Low Coverage Massively Parallel Sequencing
Copy number variations (CNVs), a common genomic mutation associated with various diseases, are important in research and clinical applications. Whole genome amplification (WGA) and massively parallel sequencing have been applied to single cell CNVs analysis, which provides new insight for the fields...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553135/ https://www.ncbi.nlm.nih.gov/pubmed/23372689 http://dx.doi.org/10.1371/journal.pone.0054236 |