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The Systemic Lupus Erythematosus IRF5 Risk Haplotype Is Associated with Systemic Sclerosis

Systemic sclerosis (SSc) is a fibrotic autoimmune disease in which the genetic component plays an important role. One of the strongest SSc association signals outside the human leukocyte antigen (HLA) region corresponds to interferon (IFN) regulatory factor 5 (IRF5), a major regulator of the type I...

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Detalles Bibliográficos
Autores principales: Carmona, F. David, Martin, Jose-Ezequiel, Beretta, Lorenzo, Simeón, Carmen P., Carreira, Patricia E., Callejas, José Luis, Fernández-Castro, Mónica, Sáez-Comet, Luis, Beltrán, Emma, Camps, María Teresa, Egurbide, María Victoria, Airó, Paolo, Scorza, Raffaella, Lunardi, Claudio, Hunzelmann, Nicolas, Riemekasten, Gabriela, Witte, Torsten, Kreuter, Alexander, Distler, Jörg H. W., Madhok, Rajan, Shiels, Paul, van Laar, Jacob M., Fonseca, Carmen, Denton, Christopher, Herrick, Ariane, Worthington, Jane, Schuerwegh, Annemie J., Vonk, Madelon C., Voskuyl, Alexandre E., Radstake, Timothy R. D. J., Martín, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553151/
https://www.ncbi.nlm.nih.gov/pubmed/23372721
http://dx.doi.org/10.1371/journal.pone.0054419