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Antibiotic Rotation for Febrile Neutropenic Patients with Hematological Malignancies: Clinical Significance of Antibiotic Heterogeneity

BACKGROUND: Our unit adopted the single administration of cefepime as the initial treatment for febrile episodes in neutropenic patients with hematological malignancies. However, recently, cefepime-resistant gram-negative bacteremia, including those with extended-spectrum β-lactamase (ESBL)-producer...

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Detalles Bibliográficos
Autores principales: Chong, Yong, Shimoda, Shinji, Yakushiji, Hiroko, Ito, Yoshikiyo, Miyamoto, Toshihiro, Kamimura, Tomohiko, Shimono, Nobuyuki, Akashi, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553165/
https://www.ncbi.nlm.nih.gov/pubmed/23372683
http://dx.doi.org/10.1371/journal.pone.0054190