Mathematical Modelling of Polyamine Metabolism in Bloodstream-Form Trypanosoma brucei: An Application to Drug Target Identification

We present the first computational kinetic model of polyamine metabolism in bloodstream-form Trypanosoma brucei, the causative agent of human African trypanosomiasis. We systematically extracted the polyamine pathway from the complete metabolic network while still maintaining the predictive capabili...

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Detalles Bibliográficos
Autores principales: Gu, Xu, Reid, David, Higham, Desmond J., Gilbert, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553166/
https://www.ncbi.nlm.nih.gov/pubmed/23372667
http://dx.doi.org/10.1371/journal.pone.0053734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553166/
https://www.ncbi.nlm.nih.gov/pubmed/23372667
http://dx.doi.org/10.1371/journal.pone.0053734

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