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Mathematical Modelling of Polyamine Metabolism in Bloodstream-Form Trypanosoma brucei: An Application to Drug Target Identification

We present the first computational kinetic model of polyamine metabolism in bloodstream-form Trypanosoma brucei, the causative agent of human African trypanosomiasis. We systematically extracted the polyamine pathway from the complete metabolic network while still maintaining the predictive capabili...

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Detalles Bibliográficos
Autores principales:	Gu, Xu, Reid, David, Higham, Desmond J., Gilbert, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553166/ https://www.ncbi.nlm.nih.gov/pubmed/23372667 http://dx.doi.org/10.1371/journal.pone.0053734

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