Accumulation of Intraneuronal β-Amyloid 42 Peptides Is Associated with Early Changes in Microtubule-Associated Protein 2 in Neurites and Synapses

Pathologic aggregation of β-amyloid (Aβ) peptide and the axonal microtubule-associated protein tau protein are hallmarks of Alzheimer's disease (AD). Evidence supports that Aβ peptide accumulation precedes microtubule-related pathology, although the link between Aβ and tau remains unclear. We p...

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Detalles Bibliográficos
Autores principales: Takahashi, Reisuke H., Capetillo-Zarate, Estibaliz, Lin, Michael T., Milner, Teresa A., Gouras, Gunnar K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553177/
https://www.ncbi.nlm.nih.gov/pubmed/23372648
http://dx.doi.org/10.1371/journal.pone.0051965

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553177/
https://www.ncbi.nlm.nih.gov/pubmed/23372648
http://dx.doi.org/10.1371/journal.pone.0051965

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